Chief Investigators

Members of our Chief Investigator Scheme

POMCTN aspires to nurture and support interested clinicians with experience in research at a local level, to progress to become grant co-applicants, members of trial clinical investigator groups and ultimately Chief Investigators.

As such we have set up our Chief Investigator Scheme to develop and mentor the CIs of tomorrow.

Current CI Scheme members were recruited through open competition in 2017 and 2018. All recruitment rounds are advertised on this website, our newsletter and on our Twitter feed.

Those wishing to register an interest in the Chief Investigator Scheme should contact us.

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Jonathan Silversides

Consultant in Critical Care and Anaesthesia
Belfast Health and Social Care Trust

Jon Silversides graduated in medicine from Queens University Belfast in 2003, and undertook specialty training in anaesthesia, and critical care in Northern Ireland, gaining FRCA, MRCP, EDIC and FFICM qualifications. He completed a fellowship in critical care in Toronto before being appointed as a Consultant in Critical Care and Anaesthesia in the Belfast Health and Social Care Trust in 2013. Jon has active research interests in both critical care and anaesthesia, and is nearing completion of a PhD on fluid therapy and deresuscitation in critical illness.


Ada Ezihe-Ejiofor

Consultant Anaesthetist
Guys & St Thomas’ Hospital NHS Foundation Trust

Ada Ezihe-Ejiofor is a Consultant Anaesthetist at Guys & St Thomas’ Hospital NHS Foundation Trust. Her specialty interests include obstetric anaesthesia, medical education and the ‘growing field’ of medical humanities. Outside of medicine her interests include writing, music, drama and film. She has produced two low budget films exploring the interface between creative media and medicine.

Denny Levett

Denny Levett

Consultant in Perioperative Medicine
Southampton University Hospital NHS Foundation trust

Denny leads the perioperative medicine service at UHS including a pre-operative CPET service, a perioperative anaemia service, a surgery school, and prehabilitation. Her clinical and research interests explore the role of exercise in pre-operative risk stratification and pre-operative optimisation to improve surgical outcomes. She is president of the Perioperative Exercise Testing and Training Society (POETTS) ( and established and chairs the National Perioperative Cardiopulmonary Exercise Testing course. She is part of the Fit 4 Surgery research group in Southampton, investigating exercise, psychological and nutritional prehabilitation and is the clinical lead for the multi-centre Wesfit Trial. She is the clinical CI for the INSPIRE trial evaluating inspiratory muscle training before surgery as a means of reducing post-operative complications.

Denny was the Association of Anaesthetists Research Fellow and her PhD thesis involved evaluating exercise capacity at up to 8000m on Mount Everest as a member of the climbing team on the Caudwell Xtreme Everest Expedition. She was the Deputy Research Leader for this altitude field study of hypoxia adaptation and the follow up expedition Xtreme Everest 2, investigating exercise efficiency in Sherpas (

Rhona G F Sinclair

Rhona Sinclair

General Anaesthetist and Perioperative Clinician
Royal Victoria Infirmary

Rhona Sinclair works as a general anaesthetist and perioperative clinician at the Royal Victoria Infirmary, Newcastle upon Tyne where she leads the preoperative assessment service. She has been involved with the local research team conducting and coordinating portfolio studies for a number of years. She has been involved in research for more than ten years and is principle investigator for a selection of locally led studies investigating fitness in surgical patients, and supervises a number of research students.

Dr Ronelle Mouton

Ronelle Mouton

Consultant Anaesthetist
Southmead Hospital

I am a consultant anaesthetist at Southmead Hospital, Bristol and an honorary senior lecturer at the University of Bristol. I have a special interest in vascular anaesthesia and am the chair of the Vascular Anaesthesia Society of Great Britain & Ireland (VASGBI). My research interests include the effect of mode of anaesthesia on perioperative outcomes, collaborative perioperative clinical trials and ischaemic preconditioning.

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Caroline Thomas

Consultant in Anaesthesia
St James University Hospital

Caroline Thomas was appointed as a Consultant in Anaesthesia at St James University Hospital, Leeds in 2017. Her clinical interests include colorectal and thoracic anaesthesia and developing perioperative services for patients undergoing major elective surgery. As a senior trainee she developed and lead trainee research groups both regionally and nationally. She is on the steering committee of a large multicentre Portfolio study and is currently PI for PQIP (Peri-Operative Quality Improvement Programme) in Leeds. Other work includes a study on the peri-operative patient experience of anxiety and she is a steering group member for the anaesthesia workstream of the Yorkshire Bowel Cancer Improvement Programme. She is an Honorary Senior Clinical Lecturer at the University of Leeds and was recently appointed as the NIHR CRN specialty lead for Anaesthesia, Peri-op Medicine and Pain for Yorkshire & the Humber.


Louise Savic

Consultant in Anaesthesia
Leeds Teaching Hospitals NHS Trust

Louise is a consultant anaesthetist in Leeds Teaching Hospitals NHS Trust. She has a clinical and research interest in drug allergy, with a focus on the prevention, management and investigation of perioperative drug allergy. She has worked in the Anaesthetic Allergy clinic in Leeds for 8 years and is a founder member of the International Suspected Perioperative Hypersensitivity Reaction group (ISPAR). Louise has a research interest in the effects of penicillin allergy on surgical outcomes and the development of novel pathways to allow preoperative de-labelling of patients. She chaired an ISPAR working party to develop consensus recommendations for the perioperative management of patients with a label of penicillin allergy, and currently chairs the British Society of Allergy and Clinical Immunology (BSACI) working party to develop national guidelines in this area. She led a penicillin de-labelling study (PADLES) and the DALES epidemiological study of drug allergy conducted by the Research and Audit Federation of Trainees (RAFT). In her clinical work she has developed a novel drug provocation service for the investigation of suspected perioperative anaphylaxis including neuromuscular blocking agent allergy.

Mandeep Phull

Mandeep Phull

Consultant in Anaesthesia and intensive care
Royal Free and University College Medical School

I graduated from Royal Free and University College Medical School and after my foundation years obtained run through training in anaesthesia. I completed a perioperative medicine fellowship at the Royal London with Professor Pearse during which time I realized that I wanted to be involved in an eventually be leading in research for the rest of my career. I am a consultant in anaesthesia and intensive care working at Barking, Havering and Redbridge University Trust. I hold a honorary senior clinical lecturer post with the William Harvey Research Institute, Queen Mary University of London. I am departmental research lead and recently have been appointed as North Thames NIHR speciality lead for anaesthesia, perioperative medicine, pain and critical care. My special interest include the high risk surgical patient, emergency surgery and perioperative critical care.


Ciara O’Donnell

Consultant Anaesthetist
Royal Victoria Hospital

Ciara O’Donnell works as a Consultant Anaesthetist in the Royal Victoria Hospital in Belfast. As a regional centre, emergency and trauma surgery including thoracic and neurosurgery form a large part of her daily job. She has a research interest in the perioperative outcomes of elderly patients with hip fracture which formed the basis of her MD in 2018. Ciara is a co-applicant and principal investigator for the NIHR funded Sugammadex for preventIoN oF pOst-operative pulmoNary complIcAtions (SINFONIA) study. As part of her research experience, she has been the primary site investigator for a GSK sponsored clinical trial and has engaged with RAFT projects such as DALES, as site lead. Ciara has collaborated with groups such as Core Outcome Measures in Effectiveness Trials (COMET) and Fragility Fracture Network UK (FFN UK). She is an Honorary Lecturer at Queen’s University Belfast.

Tom Abbott

Dr Tom Abbott

NIHR Clinical Lecturer
William Harvey Research Institute, Queen Mary University of London and Anaesthetic registrar at Barts Health NHS Trust, London, UK

Dr Abbott completed his undergraduate training at the University of Oxford and a PhD at Queen Mary University of London. He is a registrar in Anaesthesia in central London. He uses epidemiological methods to investigate the health and well-being of patients undergoing surgery, which includes interventions to improve postoperative survival and reduce perioperative complications. His research interests include perioperative myocardial injury, sub-clinical cardiac failure, cardiopulmonary exercise testing, autonomic dysfunction, postoperative pulmonary complications and the impact of COVID-19 on surgery.